Electrolyte composition of renal tubular cells in gentamicin nephrotoxicity
نویسندگان
چکیده
منابع مشابه
Gentamicin Induced Apoptosis of Renal Tubular Epithelial (LLC-PK1) Cells
Nephrotoxicity is a major limiting factor in the use of aminoglycoside antibiotics, the mechanisms for which are still speculative. To clarify the mechanisms of renal tubular cell death induced by aminoglycosides, we examined the renal proximal tubule-like cell line, LLC-PK1, after inducing apoptosis through a chronic treatment with gentamicin (GM). Changes in the expression of the Fas were als...
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*Corresponding author: Dr. Majid Tavafi, Department of anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran. E-mail: [email protected] I spite of undesirable gentamicin nephrotoxicity, this antibiotic is commonly used versus Gram-negative bacteria and still constitutes the only effective therapeutic alternative against microorganisms-pseudomonas, proteus and ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1988
ISSN: 0085-2538
DOI: 10.1038/ki.1988.118